Generation of a single-cell B cell atlas of antibody repertoires and transcriptomes to identify signatures associated with antigen specificity

Although new genomics-based pipelines have potential to augment antibody discovery, these methods remain in their infancy due to an incomplete understanding of the selection process that governs B cell clonal selection, expansion, and antigen specificity. Furthermore, it remains unknown how factors...

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Detalles Bibliográficos
Autores principales: Agrafiotis, Andreas, Neumeier, Daniel, Hong, Kai-Lin, Chowdhury, Tasnia, Ehling, Roy, Kuhn, Raphael, Sandu, Ioana, Kreiner, Victor, Cotet, Tudor-Stefan, Shlesinger, Danielle, Laslo, Daria, Anzböck, Stine, Starkie, Dale, Lightwood, Daniel J., Oxenius, Annette, Reddy, Sai T., Yermanos, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9958373/
https://www.ncbi.nlm.nih.gov/pubmed/36852274
http://dx.doi.org/10.1016/j.isci.2023.106055

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9958373/
https://www.ncbi.nlm.nih.gov/pubmed/36852274
http://dx.doi.org/10.1016/j.isci.2023.106055

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