Actin crosslinking by α-actinin averts viscous dissipation of myosin force transmission in stress fibers

Contractile force generated in actomyosin stress fibers (SFs) is transmitted along SFs to the extracellular matrix (ECM), which contributes to cell migration and sensing of ECM rigidity. In this study, we show that efficient force transmission along SFs relies on actin crosslinking by α-actinin. Upo...

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Detalles Bibliográficos
Autores principales: Katsuta, Hiroki, Okuda, Satoru, Nagayama, Kazuaki, Machiyama, Hiroaki, Kidoaki, Satoru, Kato, Masashi, Sokabe, Masahiro, Miyata, Takaki, Hirata, Hiroaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9958379/
https://www.ncbi.nlm.nih.gov/pubmed/36852278
http://dx.doi.org/10.1016/j.isci.2023.106090

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9958379/
https://www.ncbi.nlm.nih.gov/pubmed/36852278
http://dx.doi.org/10.1016/j.isci.2023.106090

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