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Rohitukine content across the geographical distribution of Dysoxylum binectariferum Hook F. and its natural derivatives as potential sources of CDK inhibitors

Dysoxylum binectariferum is an important medicinal plant distributed in the Western Ghats of India. The species has gained international importance for its anticancer component, rohitukine, a chromone alkaloid. Flavopiridol, P-276-00 and IIIM-290 are the derivatives of rohitukine in clinical trials...

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Detalles Bibliográficos
Autores principales: Varun, E., Bhakti, K., Aishwarya, K., Suraj, R Hosur, Jagadish, M.R., Mohana Kumara, P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9958448/
https://www.ncbi.nlm.nih.gov/pubmed/36852056
http://dx.doi.org/10.1016/j.heliyon.2023.e13469