Low-Density Lipoprotein Pathway Is a Ubiquitous Metabolic Vulnerability in High Grade Glioma Amenable for Nanotherapeutic Delivery

Metabolic reprogramming, through increased uptake of cholesterol in the form of low-density lipoproteins (LDL), is one way by which cancer cells, including high grade gliomas (HGG), maintain their rapid growth. In this study, we determined LDL receptor (LDLR) expression in HGGs using immunohistochem...

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Detalles Bibliográficos
Autores principales: Adekeye, Adenike O., Needham, David, Rahman, Ruman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9958636/
https://www.ncbi.nlm.nih.gov/pubmed/36839921
http://dx.doi.org/10.3390/pharmaceutics15020599

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9958636/
https://www.ncbi.nlm.nih.gov/pubmed/36839921
http://dx.doi.org/10.3390/pharmaceutics15020599

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