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Relationship between Body Composition and Serum Immunoglobulin Concentrations after Administration of Intravenous Immune Globulin–Preclinical and Clinical Evidence

The purpose of this study was to investigate the effect of obesity on immunoglobulin G (IgG) pharmacokinetics in a rat model of obesity, and to collect clinical evidence for an association between the body composition and intravenous immune globulin (IVIG) pharmacokinetic parameters in humans. In a...

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Detalles Bibliográficos
Autores principales: Brunetti, Luigi, Chapy, Helene, Nahass, Ronald G., Moore, Rebecca, Wassef, Andrew, Adler, Derek, Yurkow, Edward, Kagan, Leonid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9958704/
https://www.ncbi.nlm.nih.gov/pubmed/36839832
http://dx.doi.org/10.3390/pharmaceutics15020510