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Development of an Orthotopic HPV16-Dependent Base of Tongue Tumor Model in MHC-Humanized Mice

Head and neck squamous cell carcinomas (HNSCC) caused by infections with high-risk human papillomaviruses (HPV) are responsible for an increasing number of head and neck cancers, particularly in the oropharynx. Despite the significant biological differences between HPV-driven and HPV-negative HNSCC,...

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Detalles Bibliográficos
Autores principales: Schifflers, Christoph, Zottnick, Samantha, Förster, Jonas D., Kruse, Sebastian, Yang, Ruwen, Wiethoff, Hendrik, Bozza, Matthias, Hoppe-Seyler, Karin, Heikenwälder, Mathias, Harbottle, Richard P., Michiels, Carine, Riemer, Angelika B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9958775/
https://www.ncbi.nlm.nih.gov/pubmed/36839460
http://dx.doi.org/10.3390/pathogens12020188