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Development of an Orthotopic HPV16-Dependent Base of Tongue Tumor Model in MHC-Humanized Mice
Head and neck squamous cell carcinomas (HNSCC) caused by infections with high-risk human papillomaviruses (HPV) are responsible for an increasing number of head and neck cancers, particularly in the oropharynx. Despite the significant biological differences between HPV-driven and HPV-negative HNSCC,...
Autores principales: | Schifflers, Christoph, Zottnick, Samantha, Förster, Jonas D., Kruse, Sebastian, Yang, Ruwen, Wiethoff, Hendrik, Bozza, Matthias, Hoppe-Seyler, Karin, Heikenwälder, Mathias, Harbottle, Richard P., Michiels, Carine, Riemer, Angelika B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9958775/ https://www.ncbi.nlm.nih.gov/pubmed/36839460 http://dx.doi.org/10.3390/pathogens12020188 |
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