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Discovery of New Heterocyclic/Benzofuran Hybrids as Potential Anti-Inflammatory Agents: Design, Synthesis, and Evaluation of the Inhibitory Activity of Their Related Inflammatory Factors Based on NF-κB and MAPK Signaling Pathways

NF-κB and MAPK are classic inflammation signaling pathways which regulate inflammation signal transmission and induce the expression of many inflammatory factors. Based on the potent anti-inflammatory activity of benzofuran and its derivatives, several new heterocyclic/benzofuran hybrids were first...

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Detalles Bibliográficos
Autores principales: Chen, Yangling, Chen, Rui, Yuan, Renyikun, Huo, Lini, Gao, Hongwei, Zhuo, Youqiong, Chen, Xinxin, Zhang, Chenwei, Yang, Shilin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9958778/
https://www.ncbi.nlm.nih.gov/pubmed/36834992
http://dx.doi.org/10.3390/ijms24043575