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Cannabinoid Receptor 2 Blockade Prevents Anti-Depressive-like Effect of Cannabidiol Acid Methyl Ester in Female WKY Rats

The pathophysiology of major depressive disorder (MDD) is diverse and multi-factorial, yet treatment strategies remain limited. While women are twice as likely to develop the disorder as men, many animal model studies of antidepressant response rely solely on male subjects. The endocannabinoid syste...

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Detalles Bibliográficos
Autores principales: Hen-Shoval, Danielle, Moshe, Lital, Indig-Naimer, Talia, Mechoulam, Raphael, Shoval, Gal, Zalsman, Gil, Kogan, Natalya M., Weller, Aron
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9958868/
https://www.ncbi.nlm.nih.gov/pubmed/36835237
http://dx.doi.org/10.3390/ijms24043828