Identification of the Putative Binding Site of a Benzimidazole Opioid (Etazene) and Its Metabolites at µ-Opioid Receptor: A Human Liver Microsomal Assay and Systematic Computational Study

The synthetic benzimidazole opioid etazene (which has a 70-times higher analgesic activity than morphine), a recreational drug, has gained popularity as a novel psychoactive substance (NPS) on the illegal/darknet market; however, no experimental information is available at the molecular level on the...

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Detalles Bibliográficos
Autores principales: Chaturvedi, Krishna, Hewamanna, Isuru, Pandey, Pankaj, Khan, Washim, Wang, Yan-Hong, Chittiboyina, Amar G., Doerksen, Robert J., Godfrey, Murrell
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9959024/
https://www.ncbi.nlm.nih.gov/pubmed/36838590
http://dx.doi.org/10.3390/molecules28041601

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9959024/
https://www.ncbi.nlm.nih.gov/pubmed/36838590
http://dx.doi.org/10.3390/molecules28041601

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