Optimization and In Vitro Characterization of Telmisartan Loaded Sodium Alginate Beads and Its In Vivo Efficacy Investigation in Hypertensive Induced Animal Model

Background: Antihypertensive drug telmisartan (TEL) belongs to BCS class II, which is characterized by low water solubility and, consequently, low oral bioavailability. Gastroretentive systems may overcome the problems associated with low solubility of TEL and incomplete absorption by localizing the...

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Detalles Bibliográficos
Autores principales: Uthumansha, Ubaidulla, Prabahar, Kousalya, Gajapathy, Dilli Bhai, El-Sherbiny, Mohamed, Elsherbiny, Nehal, Qushawy, Mona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9959044/
https://www.ncbi.nlm.nih.gov/pubmed/36840031
http://dx.doi.org/10.3390/pharmaceutics15020709

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9959044/
https://www.ncbi.nlm.nih.gov/pubmed/36840031
http://dx.doi.org/10.3390/pharmaceutics15020709

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