Lipidation of Naturally Occurring α-Helical Antimicrobial Peptides as a Promising Strategy for Drug Design

In this paper, we describe the chemical synthesis, preliminary evaluation of antimicrobial properties and mechanisms of action of a novel group of lipidated derivatives of three naturally occurring α-helical antimicrobial peptides, LL-I (VNWKKVLGKIIKVAK-NH(2)), LK6 (IKKILSKILLKKL-NH(2)), ATRA-1 (KRF...

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Detalles Bibliográficos
Autores principales: Makowska, Marta, Kosikowska-Adamus, Paulina, Zdrowowicz, Magdalena, Wyrzykowski, Dariusz, Prahl, Adam, Sikorska, Emilia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9959048/
https://www.ncbi.nlm.nih.gov/pubmed/36835362
http://dx.doi.org/10.3390/ijms24043951

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9959048/
https://www.ncbi.nlm.nih.gov/pubmed/36835362
http://dx.doi.org/10.3390/ijms24043951

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