Selective α(3)β(4) Nicotinic Acetylcholine Receptor Ligand as a Potential Tracer for Drug Addiction

α(3)β(4) Nicotinic acetylcholine receptor (nAChR) has been recognized as an emerging biomarker for the early detection of drug addiction. Herein, α(3)β(4) nAChR ligands were designed and synthesized to improve the binding affinity and selectivity of two lead compounds, (S)-QND8 and (S)-T2, for the d...

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Detalles Bibliográficos
Autores principales: Kanasuwan, Apinan, Deuther-Conrad, Winnie, Chongruchiroj, Sumet, Sarasamkan, Jiradanai, Chotipanich, Chanisa, Vajragupta, Opa, Arunrungvichian, Kuntarat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9959096/
https://www.ncbi.nlm.nih.gov/pubmed/36835028
http://dx.doi.org/10.3390/ijms24043614

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9959096/
https://www.ncbi.nlm.nih.gov/pubmed/36835028
http://dx.doi.org/10.3390/ijms24043614

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