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EPHB4-RASA1-Mediated Negative Regulation of Ras-MAPK Signaling in the Vasculature: Implications for the Treatment of EPHB4- and RASA1-Related Vascular Anomalies in Humans

Ephrin receptors constitute a large family of receptor tyrosine kinases in mammals that through interaction with cell surface-anchored ephrin ligands regulate multiple different cellular responses in numerous cell types and tissues. In the cardiovascular system, studies performed in vitro and in viv...

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Detalles Bibliográficos
Autores principales: Chen, Di, Van der Ent, Martijn A., Lartey, Nathaniel L., King, Philip D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9959185/
https://www.ncbi.nlm.nih.gov/pubmed/37259315
http://dx.doi.org/10.3390/ph16020165