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Sph2((176–191)) and Sph2((446–459)): Identification of B-Cell Linear Epitopes in Sphingomyelinase 2 (Sph2), Naturally Recognized by Patients Infected by Pathogenic Leptospires

Sphingomyelin is a major constituent of eukaryotic cell membranes, and if degraded by bacteria sphingomyelinases may contribute to the pathogenesis of infection. Among Leptospira spp., there are five sphingomyelinases exclusively expressed by pathogenic leptospires, in which Sph2 is expressed during...

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Detalles Bibliográficos
Autores principales: Ataides, Laura Sant’Anna, de Moraes Maia, Fernanda, Conte, Fernando Paiva, Isaac, Lourdes, Barbosa, Angela Silva, da Costa Lima-Junior, Josué, Avelar, Kátia Eliane Santos, Rodrigues-da-Silva, Rodrigo Nunes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9959207/
https://www.ncbi.nlm.nih.gov/pubmed/36851237
http://dx.doi.org/10.3390/vaccines11020359