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SRSF3-Mediated Ki67 Exon 7-Inclusion Promotes Head and Neck Squamous Cell Carcinoma Progression via Repressing AKR1C2

Ki67 is a well-known proliferation marker with a large size of around 350 kDa, but its biological function remains largely unknown. The roles of Ki67 in tumor prognosis are still controversial. Ki67 has two isoforms generated by alternative splicing of exon 7. The roles and regulatory mechanisms of...

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Detalles Bibliográficos
Autores principales: Liu, Miaomiao, Lin, Can, Huang, Qiwei, Jia, Jun, Guo, Jihua, Jia, Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9959251/
https://www.ncbi.nlm.nih.gov/pubmed/36835286
http://dx.doi.org/10.3390/ijms24043872