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Prolonged Differentiation of Neuron-Astrocyte Co-Cultures Results in Emergence of Dopaminergic Neurons

Dopamine is present in a subgroup of neurons that are vital for normal brain functioning. Disruption of the dopaminergic system, e.g., by chemical compounds, contributes to the development of Parkinson’s disease and potentially some neurodevelopmental disorders. Current test guidelines for chemical...

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Detalles Bibliográficos
Autores principales: de Leeuw, Victoria C., van Oostrom, Conny T. M., Zwart, Edwin P., Heusinkveld, Harm J., Hessel, Ellen V. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9959280/
https://www.ncbi.nlm.nih.gov/pubmed/36835019
http://dx.doi.org/10.3390/ijms24043608