Whole-Genome Duplication and Genome Instability in Cancer Cells: Double the Trouble

Whole-genome duplication (WGD) is one of the most common genomic abnormalities in cancers. WGD can provide a source of redundant genes to buffer the deleterious effect of somatic alterations and facilitate clonal evolution in cancer cells. The extra DNA and centrosome burden after WGD is associated...

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Detalles Bibliográficos
Autores principales: Lau, Tsz Yin, Poon, Randy Y.C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9959281/
https://www.ncbi.nlm.nih.gov/pubmed/36835147
http://dx.doi.org/10.3390/ijms24043733

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9959281/
https://www.ncbi.nlm.nih.gov/pubmed/36835147
http://dx.doi.org/10.3390/ijms24043733

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