Lipid and Peptide-Oligonucleotide Conjugates for Therapeutic Purposes: From Simple Hybrids to Complex Multifunctional Assemblies

Antisense and small interfering RNA (siRNA) oligonucleotides have been recognized as powerful therapeutic compounds for targeting mRNAs and inducing their degradation. However, a major obstacle is that unmodified oligonucleotides are not readily taken up into tissues and are susceptible to degradati...

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Detalles Bibliográficos
Autores principales: Fàbrega, Carme, Aviñó, Anna, Navarro, Natalia, Jorge, Andreia F., Grijalvo, Santiago, Eritja, Ramon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9959333/
https://www.ncbi.nlm.nih.gov/pubmed/36839642
http://dx.doi.org/10.3390/pharmaceutics15020320

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9959333/
https://www.ncbi.nlm.nih.gov/pubmed/36839642
http://dx.doi.org/10.3390/pharmaceutics15020320

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