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Quiescent Cancer Cells—A Potential Therapeutic Target to Overcome Tumor Resistance and Relapse
Quiescent cancer cells (QCCs) are nonproliferating cells arrested in the G0 phase, characterized by ki67(low) and p27(high). QCCs avoid most chemotherapies, and some treatments could further lead to a higher proportion of QCCs in tumors. QCCs are also associated with cancer recurrence since they can...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9959385/ https://www.ncbi.nlm.nih.gov/pubmed/36835173 http://dx.doi.org/10.3390/ijms24043762 |