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Quiescent Cancer Cells—A Potential Therapeutic Target to Overcome Tumor Resistance and Relapse

Quiescent cancer cells (QCCs) are nonproliferating cells arrested in the G0 phase, characterized by ki67(low) and p27(high). QCCs avoid most chemotherapies, and some treatments could further lead to a higher proportion of QCCs in tumors. QCCs are also associated with cancer recurrence since they can...

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Detalles Bibliográficos
Autores principales: Lindell, Emma, Zhong, Lei, Zhang, Xiaonan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9959385/
https://www.ncbi.nlm.nih.gov/pubmed/36835173
http://dx.doi.org/10.3390/ijms24043762