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HSPs/STAT3 Interplay Sustains DDR and Promotes Cytokine Release by Primary Effusion Lymphoma Cells

Primary effusion lymphoma (PEL) is a rare and aggressive B-cell lymphoma, against which current therapies usually fail. In the present study, we show that targeting HSPs, such as HSP27, HSP70 and HSP90, could be an efficient strategy to reduce PEL cell survival, as it induces strong DNA damage, whic...

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Detalles Bibliográficos
Autores principales: Gonnella, Roberta, Arena, Andrea, Zarrella, Roberta, Gilardini Montani, Maria Saveria, Santarelli, Roberta, Cirone, Mara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9959463/
https://www.ncbi.nlm.nih.gov/pubmed/36835344
http://dx.doi.org/10.3390/ijms24043933