Critical Analysis and Optimization of Stoichiometric Ratio of Drug-Coformer on Cocrystal Design: Molecular Docking, In Vitro and In Vivo Assessment

In this present research, an attempt has been made to address the influence of drug-coformer stoichiometric ratio on cocrystal design and its impact on improvement of solubility and dissolution, as well as bioavailability of poorly soluble telmisartan. The chemistry behind cocrystallization and the...

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Detalles Bibliográficos
Autores principales: Dhibar, Manami, Chakraborty, Santanu, Basak, Souvik, Pattanayak, Paramita, Chatterjee, Tanmay, Ghosh, Balaram, Raafat, Mohamed, Abourehab, Mohammed A. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9959501/
https://www.ncbi.nlm.nih.gov/pubmed/37259428
http://dx.doi.org/10.3390/ph16020284

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9959501/
https://www.ncbi.nlm.nih.gov/pubmed/37259428
http://dx.doi.org/10.3390/ph16020284

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