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Critical Analysis and Optimization of Stoichiometric Ratio of Drug-Coformer on Cocrystal Design: Molecular Docking, In Vitro and In Vivo Assessment
In this present research, an attempt has been made to address the influence of drug-coformer stoichiometric ratio on cocrystal design and its impact on improvement of solubility and dissolution, as well as bioavailability of poorly soluble telmisartan. The chemistry behind cocrystallization and the...
Autores principales: | Dhibar, Manami, Chakraborty, Santanu, Basak, Souvik, Pattanayak, Paramita, Chatterjee, Tanmay, Ghosh, Balaram, Raafat, Mohamed, Abourehab, Mohammed A. S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9959501/ https://www.ncbi.nlm.nih.gov/pubmed/37259428 http://dx.doi.org/10.3390/ph16020284 |
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