Cargando…

N-Glycan on the Non-Consensus N-X-C Glycosylation Site Impacts Activity, Stability, and Localization of the Sd(a) Synthase B4GALNT2

The Sd(a) carbohydrate epitope and its biosynthetic B4GALNT2 enzyme are expressed in the healthy colon and down-regulated to variable extents in colon cancer. The human B4GALNT2 gene drives the expression of a long and a short protein isoform (LF-B4GALNT2 and SF-B4GALNT2) sharing identical transmemb...

Descripción completa

Detalles Bibliográficos
Autores principales: Cogez, Virginie, Vicogne, Dorothée, Schulz, Céline, Portier, Lucie, Venturi, Giulia, de Ruyck, Jérôme, Decloquement, Mathieu, Lensink, Marc F., Brysbaert, Guillaume, Dall’Olio, Fabio, Groux-Degroote, Sophie, Harduin-Lepers, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9959560/
https://www.ncbi.nlm.nih.gov/pubmed/36835549
http://dx.doi.org/10.3390/ijms24044139