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miR-199a-5p Reduces Chondrocyte Hypertrophy and Attenuates Osteoarthritis Progression via the Indian Hedgehog Signal Pathway

Osteoarthritis (OA), the most common type of arthritis, is an age-associated disease, characterized by the progressive degradation of articular cartilage, synovial inflammation, and degeneration of subchondral bone. Chondrocyte proliferation is regulated by the Indian hedgehog (IHH in humans, Ihh in...

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Detalles Bibliográficos
Autores principales: Huang, Lei, Jin, Meng, Gu, Ruiying, Xiao, Kunlin, Lu, Mengnan, Huo, Xinyu, Sun, Mengyao, Yang, Zhi, Wang, Zhiyuan, Zhang, Weijie, Zhi, Liqiang, Meng, Ziang, Ma, Jie, Ma, Jianbing, Zhang, Rui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9959662/
https://www.ncbi.nlm.nih.gov/pubmed/36835852
http://dx.doi.org/10.3390/jcm12041313