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A Key Role in Catalysis and Enzyme Thermostability of a Conserved Helix H5 Motif of Human Glutathione Transferase A1-1

Glutathione transferases (GSTs) are promiscuous enzymes whose main function is the detoxification of electrophilic compounds. These enzymes are characterized by structural modularity that underpins their exploitation as dynamic scaffolds for engineering enzyme variants, with customized catalytic and...

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Detalles Bibliográficos
Autores principales: Chronopoulou, Evangelia G., Mutabdzija, Lana, Poudel, Nirmal, Papageorgiou, Anastassios C., Labrou, Nikolaos E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9959719/
https://www.ncbi.nlm.nih.gov/pubmed/36835112
http://dx.doi.org/10.3390/ijms24043700