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A Key Role in Catalysis and Enzyme Thermostability of a Conserved Helix H5 Motif of Human Glutathione Transferase A1-1
Glutathione transferases (GSTs) are promiscuous enzymes whose main function is the detoxification of electrophilic compounds. These enzymes are characterized by structural modularity that underpins their exploitation as dynamic scaffolds for engineering enzyme variants, with customized catalytic and...
Autores principales: | Chronopoulou, Evangelia G., Mutabdzija, Lana, Poudel, Nirmal, Papageorgiou, Anastassios C., Labrou, Nikolaos E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9959719/ https://www.ncbi.nlm.nih.gov/pubmed/36835112 http://dx.doi.org/10.3390/ijms24043700 |
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