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Nanomicellar Formulations Loaded with Histamine and Paclitaxel as a New Strategy to Improve Chemotherapy for Breast Cancer

Triple negative breast cancer (TNBC) is the most aggressive breast cancer subtype. Currently, paclitaxel (PTX) represents the first-line therapy for TNBC; however it presents a hydrophobic behavior and produces severe adverse effects. The aim of this work is to improve the therapeutic index of PTX t...

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Detalles Bibliográficos
Autores principales: Nicoud, Melisa B., Ospital, Ignacio A., Táquez Delgado, Mónica A., Riedel, Jennifer, Fuentes, Pedro, Bernabeu, Ezequiel, Rubinstein, Mara R., Lauretta, Paolo, Martínez Vivot, Rocío, Aguilar, María de los Ángeles, Salgueiro, María J., Speisky, Daniela, Moretton, Marcela A., Chiappetta, Diego A., Medina, Vanina A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9959774/
https://www.ncbi.nlm.nih.gov/pubmed/36834958
http://dx.doi.org/10.3390/ijms24043546