CurQ+, a Next-Generation Formulation of Curcumin, Ameliorates Growth Plate Chondrocyte Stress and Increases Limb Growth in a Mouse Model of Pseudoachondroplasia

Mutations in cartilage oligomeric matrix protein (COMP) causes protein misfolding and accumulation in chondrocytes that compromises skeletal growth and joint health in pseudoachondroplasia (PSACH), a severe dwarfing condition. Using the MT-COMP mice, a murine model of PSACH, we showed that pathologi...

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Detalles Bibliográficos
Autores principales: Hecht, Jacqueline T., Veerisetty, Alka C., Hossain, Mohammad G., Chiu, Frankie, Posey, Karen L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9959842/
https://www.ncbi.nlm.nih.gov/pubmed/36835255
http://dx.doi.org/10.3390/ijms24043845

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9959842/
https://www.ncbi.nlm.nih.gov/pubmed/36835255
http://dx.doi.org/10.3390/ijms24043845

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