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R-DOTAP Cationic Lipid Nanoparticles Outperform Squalene-Based Adjuvant Systems in Elicitation of CD4 T Cells after Recombinant Influenza Hemagglutinin Vaccination

It is clear that new approaches are needed to promote broadly protective immunity to viral pathogens, particularly those that are prone to mutation and escape from antibody-mediated immunity. Prototypic pathogens of this type are influenza and SARS-CoV-2, where the receptor-binding protein exhibits...

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Detalles Bibliográficos
Autores principales: Henson, Thomas R., Richards, Katherine A., Gandhapudi, Siva K., Woodward, Jerold G., Sant, Andrea J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9959843/
https://www.ncbi.nlm.nih.gov/pubmed/36851752
http://dx.doi.org/10.3390/v15020538