Spanlastics as a Potential Approach for Enhancing the Nose-To-Brain Delivery of Piperine: In Vitro Prospect and In Vivo Therapeutic Efficacy for the Management of Epilepsy

The present study delineates the preparation of piperine-loaded spanlastics (PIP-SPL) to improve piperine (PIP) solubility, bioavailability, and permeation through nasal mucosa for intranasal delivery. PIP-SPL was formulated using the thin-film hydration method and optimization was performed using B...

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Detalles Bibliográficos
Autores principales: Gupta, Isha, Adin, Syeda Nashvia, Rashid, Md Abdur, Alhamhoom, Yahya, Aqil, Mohd., Mujeeb, Mohd.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9959896/
https://www.ncbi.nlm.nih.gov/pubmed/36839963
http://dx.doi.org/10.3390/pharmaceutics15020641

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9959896/
https://www.ncbi.nlm.nih.gov/pubmed/36839963
http://dx.doi.org/10.3390/pharmaceutics15020641

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