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A Highly Conserved Region in BRCA2 Suppresses the RAD51-Interaction Activity of BRC Repeats

SIMPLE SUMMARY: Mammary tumors are the most common tumor type in female dogs and one of the major problems in veterinary oncology. Breast cancer 2, early onset (BRCA2) mutations are associated with tumorigenesis in humans and dogs. BRCA2 is a DNA damage repair protein that interacts with RAD51, anot...

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Detalles Bibliográficos
Autores principales: Zhu, Zida, Kitano, Taisuke, Morimatsu, Masami, Ochiai, Kazuhiko, Ishiguro-Oonuma, Toshina, Oosumi, Kosuke, Lin, Xianghui, Orino, Koichi, Yoshikawa, Yasunaga
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9959916/
https://www.ncbi.nlm.nih.gov/pubmed/36851449
http://dx.doi.org/10.3390/vetsci10020145