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Selective Targeting of Cancer-Related G-Quadruplex Structures by the Natural Compound Dicentrine

Aiming to identify highly effective and selective G-quadruplex ligands as anticancer candidates, five natural compounds were investigated here, i.e., the alkaloids Canadine, D-Glaucine and Dicentrine, as well as the flavonoids Deguelin and Millettone, selected as analogs of compounds previously iden...

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Detalles Bibliográficos
Autores principales: Platella, Chiara, Ghirga, Francesca, Musumeci, Domenica, Quaglio, Deborah, Zizza, Pasquale, Iachettini, Sara, D’Angelo, Carmen, Biroccio, Annamaria, Botta, Bruno, Mori, Mattia, Montesarchio, Daniela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9959918/
https://www.ncbi.nlm.nih.gov/pubmed/36835480
http://dx.doi.org/10.3390/ijms24044070