Mono-ADP-ribosylation by PARP10 inhibits Chikungunya virus nsP2 proteolytic activity and viral replication

Replication of viruses requires interaction with host cell factors and repression of innate immunity. Recent findings suggest that a subset of intracellular mono-ADP-ribosylating PARPs, which are induced by type I interferons, possess antiviral activity. Moreover, certain RNA viruses, including Chik...

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Detalles Bibliográficos
Autores principales: Krieg, Sarah, Pott, Fabian, Potthoff, Laura, Verheirstraeten, Maud, Bütepage, Mareike, Golzmann, Alexandra, Lippok, Barbara, Goffinet, Christine, Lüscher, Bernhard, Korn, Patricia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9959937/
https://www.ncbi.nlm.nih.gov/pubmed/36840772
http://dx.doi.org/10.1007/s00018-023-04717-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9959937/
https://www.ncbi.nlm.nih.gov/pubmed/36840772
http://dx.doi.org/10.1007/s00018-023-04717-8

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