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Rapid profiling of DNA replication dynamics using mass spectrometry–based analysis of nascent DNA

The primary method for probing DNA replication dynamics is DNA fiber analysis, which utilizes thymidine analog incorporation into nascent DNA, followed by immunofluorescent microscopy of DNA fibers. Besides being time-consuming and prone to experimenter bias, it is not suitable for studying DNA repl...

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Detalles Bibliográficos
Autores principales: Ashour, Mohamed E., Byrum, Andrea K., Meroni, Alice, Xia, Jun, Singh, Saurabh, Galletto, Roberto, Rosenberg, Susan M., Vindigni, Alessandro, Mosammaparast, Nima
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9960042/
https://www.ncbi.nlm.nih.gov/pubmed/36795402
http://dx.doi.org/10.1083/jcb.202207121