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Rapid profiling of DNA replication dynamics using mass spectrometry–based analysis of nascent DNA
The primary method for probing DNA replication dynamics is DNA fiber analysis, which utilizes thymidine analog incorporation into nascent DNA, followed by immunofluorescent microscopy of DNA fibers. Besides being time-consuming and prone to experimenter bias, it is not suitable for studying DNA repl...
Autores principales: | Ashour, Mohamed E., Byrum, Andrea K., Meroni, Alice, Xia, Jun, Singh, Saurabh, Galletto, Roberto, Rosenberg, Susan M., Vindigni, Alessandro, Mosammaparast, Nima |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9960042/ https://www.ncbi.nlm.nih.gov/pubmed/36795402 http://dx.doi.org/10.1083/jcb.202207121 |
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