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Quantification of the Chemical Chaperone 4-Phenylbutyric Acid (4-PBA) in Cell Culture Media via LC-HRMS: Applications in Fields of Neurodegeneration and Cancer
In recent years, 4-phenylbutyric acid (4-PBA), an FDA-approved drug, has increasingly been used as a nonspecific chemical chaperone in vitro and in vitro, but its pharmacodynamics is still not clear. In this context, we developed and validated a Liquid Chromatography–High Resolution Mass Spectrometr...
Autores principales: | Villani, Salvatore, Dematteis, Giulia, Tapella, Laura, Gagliardi, Mara, Lim, Dmitry, Corazzari, Marco, Aprile, Silvio, Del Grosso, Erika |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9960049/ https://www.ncbi.nlm.nih.gov/pubmed/37259441 http://dx.doi.org/10.3390/ph16020298 |
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