Human Hematopoietic Stem Cell Engrafted IL-15 Transgenic NSG Mice Support Robust NK Cell Responses and Sustained HIV-1 Infection

Mice reconstituted with human immune systems are instrumental in the investigation of HIV-1 pathogenesis and therapeutics. Natural killer (NK) cells have long been recognized as a key mediator of innate anti-HIV responses. However, established humanized mouse models do not support robust human NK ce...

Descripción completa

Detalles Bibliográficos
Autores principales: Abeynaike, Shawn A., Huynh, Tridu R., Mehmood, Abeera, Kim, Teha, Frank, Kayla, Gao, Kefei, Zalfa, Cristina, Gandarilla, Angel, Shultz, Leonard, Paust, Silke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9960100/
https://www.ncbi.nlm.nih.gov/pubmed/36851579
http://dx.doi.org/10.3390/v15020365

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9960100/
https://www.ncbi.nlm.nih.gov/pubmed/36851579
http://dx.doi.org/10.3390/v15020365

Ejemplares similares