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Human Hematopoietic Stem Cell Engrafted IL-15 Transgenic NSG Mice Support Robust NK Cell Responses and Sustained HIV-1 Infection

Mice reconstituted with human immune systems are instrumental in the investigation of HIV-1 pathogenesis and therapeutics. Natural killer (NK) cells have long been recognized as a key mediator of innate anti-HIV responses. However, established humanized mouse models do not support robust human NK ce...

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Detalles Bibliográficos
Autores principales:	Abeynaike, Shawn A., Huynh, Tridu R., Mehmood, Abeera, Kim, Teha, Frank, Kayla, Gao, Kefei, Zalfa, Cristina, Gandarilla, Angel, Shultz, Leonard, Paust, Silke
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9960100/ https://www.ncbi.nlm.nih.gov/pubmed/36851579 http://dx.doi.org/10.3390/v15020365

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