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An in vivo phosphoregulation paradox for focal adhesions
Focal adhesions (FAs) dynamics regulate single cell migration. In this issue, Xue et al. (2023. J. Cell Biol. https://doi.org/10.1083/jcb.202206078) show that Y118 phosphorylation on Paxilin, a key FA protein, limits migration of cells in vivo. Unphosphorylated Paxilin is necessary for FA disassembl...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Rockefeller University Press
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9960130/ https://www.ncbi.nlm.nih.gov/pubmed/36795454 http://dx.doi.org/10.1083/jcb.202301060 |