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Hyperoxidized Species of Heme Have a Potent Capacity to Induce Autoreactivity of Human IgG Antibodies

The interaction of some human antibodies with heme results in posttranslational acquisition of binding to various self- and pathogen-derived antigens. The previous studies on this phenomenon were performed with oxidized heme (Fe(3+)). In the present study, we elucidated the effect of other pathologi...

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Detalles Bibliográficos
Autores principales: Wiatr, Marie, Hadzhieva, Maya, Lecerf, Maxime, Noé, Rémi, Justesen, Sune, Lacroix-Desmazes, Sébastien, Dragon-Durey, Marie-Agnès, Dimitrov, Jordan D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9960230/
https://www.ncbi.nlm.nih.gov/pubmed/36834827
http://dx.doi.org/10.3390/ijms24043416