Cargando…

Lethal Caspase-1/4-Dependent Injury Occurs in the First Minutes of Coronary Reperfusion and Requires Calpain Activity

To study the relationship between caspase-1/4 and reperfusion injury, we measured infarct size (IS) in isolated mouse hearts undergoing 50 min global ischemia/2 h reperfusion. Starting VRT-043198 (VRT) at reperfusion halved IS. The pan-caspase inhibitor emricasan duplicated VRT’s protection. IS in c...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yang, Xi-Ming, Cohen, Michael V., Sayner, Sarah, Audia, Jonathon P., Downey, James M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9960231/ https://www.ncbi.nlm.nih.gov/pubmed/36835212 http://dx.doi.org/10.3390/ijms24043801

Ejemplares similares

Inhibition of calpain but not caspase activity by spectrin fragments
por: Rolius, Ramunas, et al.
Publicado: (2010)

TRIF signaling is required for caspase-11-dependent immune responses and lethality in sepsis
por: Tang, Yiting, et al.
Publicado: (2018)

Cardioprotective effects of Prolame and SNAP are related with nitric oxide production and with diminution of caspases and calpain-1 activities in reperfused rat hearts
por: Román-Anguiano, Nadia Giovanna, et al.
Publicado: (2019)

Calpain: the regulatory point of myocardial ischemia-reperfusion injury
por: Liu, Guo-Yang, et al.
Publicado: (2023)

Contribution of Calpain and Caspases to Cell Death in Cultured Monkey RPE Cells
por: Nakajima, Emi, et al.
Publicado: (2017)

Calpain is required for macroautophagy in mammalian cells
por: Demarchi, Francesca, et al.
Publicado: (2006)

Lethal and Non-Lethal Functions of Caspases in the DNA Damage Response
por: Lopez, Karla E., et al.
Publicado: (2022)

The Calpain, Caspase 12, Caspase 3 Cascade Leading to Apoptosis Is Altered in F508del-CFTR Expressing Cells
por: Kerbiriou, Mathieu, et al.
Publicado: (2009)

Dual vulnerability of tau to calpains and caspase-3 proteolysis under neurotoxic and neurodegenerative conditions
por: Cheng Liu, Ming, et al.
Publicado: (2011)

Calpain-mediated protein targets in cardiac mitochondria following ischemia–reperfusion
por: Li, Ling, et al.
Publicado: (2022)

Calpains in cyanobacteria and the origin of calpains
por: Vešelényiová, Dominika, et al.
Publicado: (2022)

A Membrane Potential- and Calpain-Dependent Reversal of Caspase-1 Inhibition Regulates Canonical NLRP3 Inflammasome
por: Zhang, Yifei, et al.
Publicado: (2018)

m-Calpain is required for preimplantation embryonic development in mice
por: Dutt, Previn, et al.
Publicado: (2006)

Mycobacterium fortuitum-induced ER-Mitochondrial calcium dynamics promotes calpain/caspase-12/caspase-9 mediated apoptosis in fish macrophages
por: Datta, Debika, et al.
Publicado: (2018)

Cross-Talk between Two Cysteine Protease Families: Activation of Caspase-12 by Calpain in Apoptosis
por: Nakagawa, Toshiyuki, et al.
Publicado: (2000)

Secretion of IL-16 through TNFR1 and calpain-caspase signaling contributes to MRSA pneumonia
por: Ahn, Danielle, et al.
Publicado: (2014)

Activation of Cytosolic Calpain, Not Caspase, Is Underlying Mechanism for Hypoxic RGC Damage in Human Retinal Explants
por: Kobayashi-Otsugu, Momoko, et al.
Publicado: (2020)

Calpain-3 Is Not a Sodium Dependent Protease and Simply Requires Calcium for Activation
por: Wette, Stefan G., et al.
Publicado: (2023)

Calpain and Reactive Oxygen Species Targets Bax for Mitochondrial Permeabilisation and Caspase Activation in Zerumbone Induced Apoptosis
por: Sobhan, Praveen K., et al.
Publicado: (2013)

Inherited Retinal Degeneration: PARP-Dependent Activation of Calpain Requires CNG Channel Activity
por: Yan, Jie, et al.
Publicado: (2022)

CaMKII/calpain interaction mediates ischemia/reperfusion injury in isolated rat hearts
por: Lu, Hong-Ting, et al.
Publicado: (2020)

Calpain-2 participates in the process of calpain-1 inactivation
por: Shinkai-Ouchi, Fumiko, et al.
Publicado: (2020)

The role of the Hsp90/Akt pathway in myocardial calpain-induced caspase-3 activation and apoptosis during sepsis
por: Li, Xiaoping, et al.
Publicado: (2013)

EphrinB/EphB signaling contributes to spinal nociceptive processing via calpain-1 and caspase-3
por: Yang, Mei, et al.
Publicado: (2018)

Correction: Calpain and Reactive Oxygen Species Targets Bax for Mitochondrial Permeabilisation and Caspase Activation in Zerumbone Induced Apoptosis
por: Sobhan, Praveen K., et al.
Publicado: (2022)

Hippocampal calpain is required for the consolidation and reconsolidation but not extinction of contextual fear memory
por: Nagayoshi, Taikai, et al.
Publicado: (2017)

Calpain 2-mediated autophagy defect increases susceptibility of fatty livers to ischemia–reperfusion injury
por: Zhao, Q, et al.
Publicado: (2016)

Calpain cleavage and inactivation of the sodium calcium exchanger-3 occur downstream of Aβ in Alzheimer’s disease
por: Atherton, Joe, et al.
Publicado: (2014)

Bacterial calpains and the evolution of the calpain (C2) family of peptidases
por: Rawlings, Neil D.
Publicado: (2015)

Novel calpain families and novel mechanisms for calpain regulation in Aplysia
por: Hastings, Margaret H., et al.
Publicado: (2017)

Commentary on: Calpain-2 participates in the process of calpain-1 inactivation
por: Kumari, Raniki, et al.
Publicado: (2021)

Calpain-1 and Calpain-2 in the Brain: New Evidence for a Critical Role of Calpain-2 in Neuronal Death
por: Wang, Yubin, et al.
Publicado: (2020)

Glutamate-induced apoptosis in neuronal cells is mediated via caspase-dependent and independent mechanisms involving calpain and caspase-3 proteases as well as apoptosis inducing factor (AIF) and this process is inhibited by equine estrogens
por: Zhang, YueMei, et al.
Publicado: (2006)

Calpain-1 and Calpain-2 in the Brain: Dr. Jekill and Mr Hyde?
por: Baudry, Michel
Publicado: (2019)

Perturbation with Intrabodies Reveals That Calpain Cleavage Is Required for Degradation of Huntingtin Exon 1
por: Southwell, Amber L., et al.
Publicado: (2011)

RIP3 mediates the embryonic lethality of caspase-8-deficient mice
por: Kaiser, William J., et al.
Publicado: (2011)

Interactome disassembly during apoptosis occurs independent of caspase cleavage
por: Scott, Nichollas E, et al.
Publicado: (2017)

Pharmacological Inhibition of Caspase and Calpain Proteases: A Novel Strategy to Enhance the Homing Responses of Cord Blood HSPCs during Expansion
por: V. M., Sangeetha, et al.
Publicado: (2012)

Role of Calpain in Apoptosis
por: Momeni, Hamid Reza
Publicado: (2011)

Role of Gate-16 and Gabarap in Prevention of Caspase-11-Dependent Excess Inflammation and Lethal Endotoxic Shock
por: Sakaguchi, Naoya, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_ak026g3h4sa098oirkumsjhvjk