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The genetic background shapes the susceptibility to mitochondrial dysfunction and NASH progression

Non-alcoholic steatohepatitis (NASH) is a global health concern without treatment. The challenge in finding effective therapies is due to the lack of good mouse models and the complexity of the disease, characterized by gene–environment interactions. We tested the susceptibility of seven mouse strai...

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Detalles Bibliográficos
Autores principales: Benegiamo, Giorgia, von Alvensleben, Giacomo V.G., Rodríguez-López, Sandra, Goeminne, Ludger J.E., Bachmann, Alexis M., Morel, Jean-David, Broeckx, Ellen, Ma, Jing Ying, Carreira, Vinicius, Youssef, Sameh A., Azhar, Nabil, Reilly, Dermot F., D’Aquino, Katharine, Mullican, Shannon, Bou-Sleiman, Maroun, Auwerx, Johan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9960245/
https://www.ncbi.nlm.nih.gov/pubmed/36787127
http://dx.doi.org/10.1084/jem.20221738