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The genetic background shapes the susceptibility to mitochondrial dysfunction and NASH progression
Non-alcoholic steatohepatitis (NASH) is a global health concern without treatment. The challenge in finding effective therapies is due to the lack of good mouse models and the complexity of the disease, characterized by gene–environment interactions. We tested the susceptibility of seven mouse strai...
Autores principales: | Benegiamo, Giorgia, von Alvensleben, Giacomo V.G., Rodríguez-López, Sandra, Goeminne, Ludger J.E., Bachmann, Alexis M., Morel, Jean-David, Broeckx, Ellen, Ma, Jing Ying, Carreira, Vinicius, Youssef, Sameh A., Azhar, Nabil, Reilly, Dermot F., D’Aquino, Katharine, Mullican, Shannon, Bou-Sleiman, Maroun, Auwerx, Johan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9960245/ https://www.ncbi.nlm.nih.gov/pubmed/36787127 http://dx.doi.org/10.1084/jem.20221738 |
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