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Effects of a Soluble Guanylate Cyclase Stimulator Riociguat on Contractility of Isolated Pulmonary Artery and Hemodynamics of U46619-Induced Pulmonary Hypertension in Dogs

SIMPLE SUMMARY: Pulmonary hypertension (PH) is a progressive and refractory vascular disease in both dogs and humans. The soluble guanylate cyclase stimulator riociguat is a relatively novel pulmonary vasodilator used for the treatment of PH in human medicine. Although riociguat may have beneficial...

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Detalles Bibliográficos
Autores principales: Kameshima, Satoshi, Nakamura, Yuki, Uehara, Kenji, Kodama, Tomoko, Yamawaki, Hideyuki, Nishi, Kotaro, Okano, Shozo, Niijima, Ryo, Kimura, Yuya, Itoh, Naoyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9960282/
https://www.ncbi.nlm.nih.gov/pubmed/36851463
http://dx.doi.org/10.3390/vetsci10020159