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Extracellular Vesicle Treatment Alleviates Neurodevelopmental and Neurodegenerative Pathology in Cortical Spheroid Model of Down Syndrome

Down syndrome (DS), or trisomy 21, is manifested in a variety of anatomical and cellular abnormalities resulting in intellectual deficits and early onset of Alzheimer’s disease (AD) with no effective treatments available to alleviate the pathologies associated with the disorder. The therapeutic pote...

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Detalles Bibliográficos
Autores principales: Campbell, Natalie Baker, Patel, Yesha, Moore, Tara L., Medalla, Maria, Zeldich, Ella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9960302/
https://www.ncbi.nlm.nih.gov/pubmed/36834891
http://dx.doi.org/10.3390/ijms24043477