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STING Agonist-Induced Skin Inflammation Is Exacerbated with Prior Systemic Innate Immune Activation

Activation of the Stimulator of Interferon Genes (STING) protein has paradoxical outcomes in skin disease. STING activation exacerbates psoriatic skin disease and delays wound healing in diabetic mice, yet it also facilitates wound healing in normal mice. To address the role of localized STING activ...

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Detalles Bibliográficos
Autores principales: Pyclik, Marcelina, Durslewicz, Justyna, Papinska, Joanna A., Deshmukh, Umesh S., Bagavant, Harini
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9960435/
https://www.ncbi.nlm.nih.gov/pubmed/36835537
http://dx.doi.org/10.3390/ijms24044128