In Vivo Evaluation of Thiamine Hydrochloride with Gastro-Retentive Drug Delivery in Healthy Human Volunteers Using Gamma Scintigraphy

A floating tablet system containing thiamine hydrochloride, a model drug with a narrow absorption window, was evaluated. The tablet was found to have a floating lag time of less than 30 s with a sustained drug release over 12 h during in vitro dissolution studies. The gastro-retentive property of th...

Descripción completa

Detalles Bibliográficos
Autores principales: Kam, Li-Ying, Wong, Jia-Woei, Yuen, Kah-Hay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9960539/
https://www.ncbi.nlm.nih.gov/pubmed/36840013
http://dx.doi.org/10.3390/pharmaceutics15020691

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9960539/
https://www.ncbi.nlm.nih.gov/pubmed/36840013
http://dx.doi.org/10.3390/pharmaceutics15020691

Ejemplares similares