Biological Effects in Cancer Cells of Mono- and Bidentate Conjugation of Cisplatin on PAMAM Dendrimers: A Comparative Study

Cisplatin (cis-diamminedichloroplatinum(II)) is a potent chemotherapeutic agent commonly used to treat cancer. However, its use also leads to serious side effects, such as nephrotoxicity, ototoxicity, and cardiotoxicity, which limit the dose that can be safely administered to patients. To minimize t...

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Detalles Bibliográficos
Autores principales: Camacho, Cláudia, Maciel, Dina, Tomás, Helena, Rodrigues, João
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9960565/
https://www.ncbi.nlm.nih.gov/pubmed/36840012
http://dx.doi.org/10.3390/pharmaceutics15020689

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9960565/
https://www.ncbi.nlm.nih.gov/pubmed/36840012
http://dx.doi.org/10.3390/pharmaceutics15020689

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